A double-blind study in 20 human volunteers showed a fourfold increase in antibody response to pneumococcal vaccine in those receiving DMG orally as compared with controls ( P < 0.01). Its potential as an immunoadjuvant has also been suggested by a study of an analog of DMG, calcium pangamate. Dimethylglycine (DMG), a tertiary amino acid, has had wide acceptance as a nonfuel nutrient presumably it enhances oxygen utilization by tissue and complexes free radicals.
